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Consult with your doctor before you receive any vaccine. Avoid receiving a live vaccine (eg, measles, mumps) while you are using Prednisolone..
It is recommended to carry an id card that says you take prednisolone if you are using prednisolone regularly. Be aware that Tramadol may interact with some medicines. Consult with your health care provider in case you are taking any other drugs, especially any of the following: carbamazepine because it may decrease Tramadol 's effectiveness and increase the risk of seizures; certain medicines for mental or mood disorders (eg, olanzapine, haloperidol), cyclobenzaprine, isoniazid, other opioid pain medicine (eg, codeine, hydrocodone), phenothiazines (eg, promethazine), sleeping medicines (eg, zolpidem), sodium oxybate (GHB), tricyclic antidepressants (amitriptyline), or weight loss medicines (eg, phentermine) because side effects, including excessive drowsiness, trouble breathing, liver problems, or seizures, may be increased; furazolidone, monoamine oxidase (MAO) inhibitors (eg, phenelzine), nefazodone, selegiline, or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because they may cause serious and sometimes fatal reactions, including restlessness, fever, excessive sweating, confusion, twitching, and seizures; oral anticoagulants (eg, warfarin) because its side effects, including bleeding, may be increased by Tramadol; digoxin because the risk of side effects, including nausea, vomiting, or slow heartbeat, may be increased by Tramadol.

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